Domino Mail File Reporter

I have done multiple EV installs for Exchnage but not for Domino. Where should the DMFR tool be ran, on the Domino servers or a remote system? Also, if the Domino servers are clustered, should it be ran against only the active nodes? Will there be  a performance impact from running this tool? The customer has 8500 mailboxes.

Thanks for any assistance.

Ray